What is Fine-Needle Aspiration Cytology?

Fine-Needle Aspiration Cytology (FNAC) is a minimally invasive diagnostic procedure used to extract a small sample of cells from a lump, mass or abnormal tissue in the body. It involves the use of a very thin, hollow needle to collect cells, which are then analysed under a microscope to determine their characteristics. 

FNAC is widely used to evaluate suspicious growths or masses that can occur in various parts of the body, including the thyroid and lymph nodes. It is often guided by imaging techniques such as ultrasound or computed tomography (CT) scans to ensure precision, especially for deeper or less accessible areas​. 

This procedure is performed for both diagnostic and therapeutic purposes. Diagnostically, FNAC helps in the early detection of conditions like cancer, cysts, infections, and other non-cancerous growths such as lipomas (insert link to service page) or fibroadenomas. By extracting a small sample of tissue or fluid, pathologists can determine whether a mass is benign (non-cancerous) or malignant (cancerous)​. 

In some cases, FNAC is also used to assess the effectiveness of treatment for known tumours or to identify markers that can guide further cancer therapy​. Therapeutically, FNAC can be used to drain abscesses or fluid-filled cysts, which can offer relief in cases where fluid buildup causes discomfort. It is a preferred option in cosmetically sensitive areas, such as the breast, as it avoids large incisions and leaves minimal scarring​.

Fine-Needle Aspiration Cytology (FNAC) is a minimally invasive diagnostic procedure used to collect and analyse cells from suspicious lumps or masses in the body.

How does Fine-Needle Aspiration Cytology work?

Fine-Needle Aspiration Cytology (FNAC) works by using a thin, hollow needle to extract a small sample of cells from a suspicious lump, mass or fluid-filled area in the body. The procedure begins by cleaning the skin at the biopsy site with an antiseptic solution, and local anesthesia may be applied to minimise discomfort. Once the area is prepared, a fine needle is inserted into the lump or tissue, sometimes guided by imaging technologies like ultrasound or CT scans to ensure accuracy, especially for deeper masses. 

The needle is moved back and forth within the mass, while a syringe applies suction to extract cells or fluid. Multiple samples may be taken if necessary to ensure adequate cell collection. These samples are then placed on glass slides, stained, and examined under a microscope by a pathologist to identify whether the cells are benign, malignant, or indicative of other conditions like infections or cysts. The entire procedure typically takes a few minutes, and the patient can often resume normal activities shortly after.

What are the benefits of Fine-Needle Aspiration Cytology?

Fine-Needle Aspiration Cytology (FNAC) offers numerous advantages as a diagnostic tool. Its minimally invasive nature and quick turnaround make it a popular choice for evaluating suspicious lumps and masses. FNAC is particularly valuable because it provides crucial information while minimising patient discomfort– making it ideal for both early diagnosis and ongoing monitoring of various conditions. Here are some of the key benefits:

  • Minimally invasive, as it requires only a small needle insertion.
  • Provides rapid diagnostic results, often within a few days.
  • Can be performed on an outpatient basis with minimal recovery time.
  • Reduces the need for more invasive surgical biopsies.
  • Helps diagnose a wide range of conditions, including cancer, infections, and benign masses.
  • Can be used with imaging guidance to access deeper or less accessible areas.
  • Causes minimal scarring and has a low risk of complications.
  • Cost-effective compared to other diagnostic methods like open biopsies​.

What conditions can Fine-Needle Aspiration Cytology diagnose/treat? 

Fine-Needle Aspiration Cytology (FNAC) is used to diagnose a wide range of medical conditions by analysing cells extracted from suspicious masses or tissues. It is commonly used in both diagnostic and therapeutic settings to provide crucial information about the nature of a lump or mass. FNAC can be used to diagnose or treat the following conditions:

Fine-Needle Aspiration Cytology (FNAC) is commonly used to evaluate thyroid nodules, helping to determine whether they are benign or malignant by analyzing a small sample of cells​
  • Cancer: FNAC helps in identifying malignant cells in various types of cancer, including breast cancer and , thyroid cancer  , and lymphomas.
  • Benign tumours: it can detect non-cancerous growths like lipomas or fibroadenomas.
  • Infections: FNAC can diagnose infections such as bacterial infections, including abscesses and infections in lymph nodes.
  • Cysts: it is used to assess and, in some cases, drain fluid-filled cysts.
  • Thyroid nodules: FNAC is frequently used to evaluate nodules in the thyroid gland, determining whether they are benign or malignant.
  • Lymph node abnormalities: it can help diagnose enlarged lymph nodes, determining whether they are reactive (due to infection) or cancerous.
  • Lung conditions: FNAC is used for lung biopsies to assess suspicious masses or diagnose conditions like lung cancer.
  • Pancreatic disorders: it aids in diagnosing tumours or cysts in the pancreas.

What results can I expect from Fine- Needle Aspiration Cytology?

Fine-Needle Aspiration Cytology (FNAC) procedure is quick and minimally invasive, which typically takes just a few minutes. After the cells are collected, they will be sent to a laboratory for analysis by a pathologist. 

Within a few days, your doctor will receive the results, which generally fall into one of three categories: benign (non-cancerous), malignant (cancerous), or indeterminate (unclear results that may require further testing or biopsy). Your doctor will carefully explain the results to you and discuss the next steps, whether it’s monitoring a benign mass, starting treatment for a malignancy, or conducting additional tests if the findings are inconclusive​. 

If you are concerned about a suspicious lump or swelling, schedule an appointment with NC Tan Surgery to assess if Fine-Needle Aspiration Cytology (FNAC) is feasible to get you a definitive diagnosis.

How many FNAC sessions are needed?

The number of Fine-Needle Aspiration Cytology (FNAC) sessions typically depends on the specific condition being evaluated and the adequacy of the sample collected. In most cases, only one FNAC session is required to obtain sufficient cells for diagnosis. However, if the initial sample is inconclusive or inadequate, your doctor may recommend a follow-up FNAC session. For certain deeper or more complex masses, imaging-guided FNAC may be used to improve accuracy, and in rare cases, multiple sessions may be needed to collect sufficient cells from different areas of the mass.

Frequently Asked Questions

FNAC is generally well-tolerated with minimal discomfort. A local anesthetic may be applied to numb the area, and while you might feel a slight pinch or pressure, most people report the pain as mild.

In most cases, no special preparation is needed, but your doctor may advise avoiding food or drinks if the procedure involves sedation. Always follow specific instructions from your healthcare provider.

The actual procedure typically takes about 10 to 20 minutes, although you might spend a little more time in the clinic for preparation and post-procedure observation.

Yes, if you haven’t received sedatives, you can drive yourself home. If sedation was used, it’s best to arrange for someone to drive you.

FNAC is considered very safe, with minor risks such as bruising, bleeding, or infection at the needle site. Major complications are rare, and your doctor will provide guidelines for post-procedure care.

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